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The National Institutes of Health
NEUROSCIENCE RESEARCH SUPPORT AT THE NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

NEUROSCIENCE RESEARCH SUPPORT AT THE NICHD

DEVELOPMENTAL BIOLOGY, GENETICS &TERATOLOGY (DBGT) BRANCH
URL: http://www.nichd.nih.gov/crmc/dbgt

• Normal and abnormal development of the central and peripheral nervous systems
• Neurogenesis, cell migration, differentiation, guidance, synapse formation, role of growth and other factors in neural development
• Neural tube formation/defects
• Neurodevelopmental teratogens
• Mechanisms underlying neural development
• Multidisciplinary approaches include animal models, genetics, molecular biology, cell biology
  Contact: Deborah Henken, 301-496-5541 E-mail: dh50g@nih.gov

ENDOCRINOLOGY, NUTRITION & GROWTH (ENG) BRANCH
URL: http://www.nichd.nih.gov/crmc/eng

• Nutritional effects on brain development
• Neurotropic growth factors in neuronal function, connectivity and overall brain development
• Neuroendocrinology
• Sexual dimorphism of the nervous system
• Innervation of endocrine organs
  Contact: Gilman Grave, 301-496-5593 E-mail: gg37v@nih.gov

MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES (MRDD) BRANCH
URL: http://www.nichd.nih.gov/crmc/mrdd

• Etiology and pathophysiology of abnormal brain development and function
• Screening, diagnosis, treatment and management of MRDD
• Particular disorders include Down syndrome, Fragile X syndrome, Rett Syndrome, autism, self-injurious behavior, inborn errors of metabolism, etc.
• Approaches include molecular genetics, animal models, behavioral interventions, gene therapy
  Contact: MaryLou Oster-Granite, 301-435-6866
  E-mail: mo96o@nih.gov

NATIONAL CENTER FOR MEDICAL REHABILITATION RESEARCH (NCMRR)
URL: http://www.nichd.nih.gov/about/ncmrr

• Pathophysiology and management of the chronically injured nervous system (including stroke, traumatic brain injury, spinal cord injury, and neurological disorders)
• Repair and recovery of motor and cognitive function, functional plasticity and adaptation, and windows of opportunity for rehabilitative interventions
• Rehabilitative strategies involving pharmaceutical approaches, exercise, motor training, and behavioral modifications
• Secondary conditions associated with chronic disabilities
• Improved diagnosis, assessment, and outcome measures
• Development of orthotics, prosthetics, and other assistive technologies
  Contact: Ralph M. Nitkin, 301-402-2242 E-mail: rn21e@nih.gov

REPRODUCTIVE SCIENCES (RS) BRANCH
URL: http://www.nichd.nih.gov/cpr/rs

• Neuroendocrine control of reproduction including the cellular and molecular mechanisms within the brain governing ovulation and gametogenesis
• Genetics of reproductive neuroendocrine diseases and disorders
• Neural basis of reproductive behavior, sex function and sex differentiation
• Neuro-immune-endocrine axis in fertility regulation
• Effects on reproduction of photoperiod, circadian rhythms and appetite control
• Basic and clinical approaches include the development of animal models through genetic engineering, cell/tissue culture, imaging techniques, tissue transplantation
  Contact: Louis DePaolo, 301-496-6515 E-mail: ld38p@nih.gov

CHILD DEVELOPMENT & BEHAVIOR (CDB) BRANCH
URL: http://www.nichd.nih.gov/crmc/cdb

• Basic developmental behavioral and cognitive neuroscience in humans and animal models
• Neuroanatomical and neuroendocrine bases of behavior
• Developmental behavioral neurotoxicology
• Neural basis of language, cognitive, learning, memory, sensory, motor and perceptual development
• Screening, diagnosis, and treatment of learning disabilities, attention and language disorders
• Multidisciplinary approaches include behavioral and molecular genetics, behavioral and cognitive interventions, structural and functional neuroimaging and electrophysiology
  Contact: Lisa Freund, 301-435-6879 E-mail: freundl@mail.nih.gov

PREGNANCY AND PERINATOLOGY (PP) BRANCH
URL: http://www.nichd.nih.gov/crmc/pp

• Management of maternal neurologic risk during pregnancy and effects of therapies on the fetus
• Neurochemical control of labor, fetal neuroendocrine system
• Pathogenesis and prevention of neurologic sequelae of preterm birth, intrauterine growth retardation, asphyxia of the term newborn, transplacental effects of toxicants
• Tools to assess fetal, neonatal, and infant neurologic and behavioral maturity
• Development and regulation of cardiorespiratory control and sleep states in infancy, neurologic deficits in SIDS Contact: Marian Willinger, 301-496-5575
  E-mail: mw75q@nih.gov

The National Institute of Child Health and Human Development is committed to supporting research in the neurosciences, particularly as it affects developing systems and rehabilitation. The NICHD spends approximately 25% of its research funds on basic, clinical and/or behavioral research in this arena Within this context, the Institute has primary responsibility for projects relating to maternal and child health and human development, reproduction, developmental biology, clinical nutrition, perinatal and infant morbidity and mortality, mental retardation and developmental disabilities, pediatric and maternal AIDS, and medical rehabilitation

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